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Linear Mixed Models for Longitudinal Data | 
enlarge | Authors: Geert Verbeke, Geert Molenberghs Publisher: Springer Category: Book
List Price: $99.00 Buy New: $69.67 You Save: $29.33 (30%)
New (25) Used (14) from $69.00
Rating: 3 reviews Sales Rank: 498457
Media: Hardcover Edition: Corrected Pages: 608 Number Of Items: 1 Shipping Weight (lbs): 2.1 Dimensions (in): 9.3 x 6.4 x 1.2
ISBN: 0387950273 Dewey Decimal Number: 519 EAN: 9780387950273
Publication Date: May 25, 2001 Availability: Usually ships in 1-2 business days Shipping: Expedited shipping available Shipping: International shipping available Condition: New Book. International Shipping Available
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Product Description This book provides a comprehensive treatment of linear mixed models for continuous longitudinal data. Next to model formulation, this edition puts major emphasis on exploratory data analysis for all aspects of the model, such as the marginal model, subject-specific profiles, and residual covariance structure. Further, model diagnostics and missing data receive extensive treatment. Sensitivity analysis for incomplete data is given a prominent place. Several variations to the conventional linear mixed model are discussed (a heterogeity model, condional linear mid models). This book will be of interest to applied statisticians and biomedical researchers in industry, public health organizations, contract research organizations, and academia. The book is explanatory rather than mathematically rigorous. Most analyses were done with the MIXED procedure of the SAS software package, and many of its features are clearly elucidated. How3ever, some other commercially available packages are discussed as well. Great care has been taken in presenting the data analyses in a software-independent fashion. Geert Verbeke is Assistant Professor at the Biostistical Centre of the Katholieke Universiteit Leuven in Belgium. He received the B.S. degree in mathematics (1989) from the Katholieke Universiteit Leuven, the M.S. in biostatistics (1992) from the Limburgs Universitair Centrum, and earned a Ph.D. in biostatistics (1995) from the Katholieke Universiteit Leuven. Dr. Verbeke wrote his dissertation, as well as a number of methodological articles, on various aspects of linear mixed models for longitudinal data analysis. He has held visiting positions at the Gerontology Research Center and the Johns Hopkins University. Geert Molenberghs is Assistant Professor of Biostatistics at the Limburgs Universitair Centrum in Belgium. He received the B.S. degree in mathematics (1988) and a Ph.D. in biostatistics (1993) from the Universiteit Antwerpen. Dr. Molenberghs published methodological work on the analysis of non-response in clinical and epidemiological studies. He serves as an associate editor for Biometrics, Applied Statistics, and Biostatistics, and is an officer of the Belgian Statistical Society. He has held visiting positions at the Harvard School of Public Health.
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| Customer Reviews:
excellent for applications to clinical trials data with some missing data February 8, 2008 Michael R. Chernick (Holland PA) 28 out of 28 found this review helpful
This book is basically an update of their 1997 mongraph. Longitudinal data are important in biostatistics and particularly in the analysis of clinical trials. There are effective methods for handling longitudinal data using linear models with covariance structures that represent the time dependence of the repeated observations. There are many subtle issues in the analysis and many who analyze longitudinal data apply incorrect linear models and are often not aware of the consequences of their decisions. The authors were motivated to provide a reference source to remedy this problem. The book presents the theory and applications and uses SAS Proc Mixed as a vehicle for presenting many of the results in a clear and understandable fashion. An important feature of the book is its emphasis on how best to deal with the problem of missing data. This is covered in chapters 14 - 16. Although SAS is emphasized throughout the book other software tools are also illustrated in Appendix A (including SPlus). SUDAAN is a package produced by the Research Triangle Institute in North Carolina that also handles longitudinal data but is overlooked by the authors. Another great book on longitudinal data analysis is Diggle, Liang and Zeger "Analysis of Longitudinal Data" published in 1994. There have been many advances since 1994 and Verbeke and Molenberghs cover a great deal of it. You can find my review of Diggle, Liang and Zeger on Amazon. An updated second edition of their book has now appeared and is more up-to-date. I find this book by Verbeke and Molenberghs one of the best and most innovative on this topic. Another nice addition is the new book on missing data in clinical studies by Molenberghs and Kennard. I have written an amazon trview on that one also.
thorough treatment of linear mixed models September 21, 2000 Michael R. Chernick (Malvern, PA) 27 out of 29 found this review helpful
This book is basically an update of their 1997 mongraph. Longitudinal data are important in biostatistics and particularly in the analysis of clinical trials. There are effective methods for handling longitudinal data using linear models with covariance structures that represent the time dependence of the repeated observations. There are many subtle issues in the analysis and many who analyze longitudinal data apply incorrect linear models and are often not aware of the consequences of their decisions. The authors were motivated to provide a reference source to remedy this problem. The book presents the theory and applications and uses SAS Proc Mixed as a vehicle for presenting many of the results in a clear and understandable fashion. An important feature of the book is its emphasis on how best to deal with the problem of missing data. This is covered in chapters 14 - 16. Although SAS is emphasized throughout the book other software tools are also illustrated in Appendix A (including SPlus). SUDAAN is a package produced by the Research Triangle Institute in North Carolina that also handles longitudinal data but is overlooked by the authors. Another great book on longitudinal data analysis is Diggle, Liang and Zeger "Analysis of Longitudinal Data" published in 1994. There have been many advances since 1994 and Verbeke and Molenberghs cover a great deal of it. You can find my review of Diggle, Liang and Zeger on Amazon. An updated second edition of their book is in the works and will probably appear in 2001.
Excellent book March 8, 2007 Savvas Papadopoulos (Greece) 6 out of 7 found this review helpful
The book covers many advanced topics of Longitudinal data with many examples and SAS programs. Congatulations to the authors for this outstanding job. Savas Papadopoulos
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